Nutlin-3 CAS：890090-75-2

Nutlin-3,also known as(±)-Nutlin-3 and N-6287,is a p53-Mdm2 Antagonist for Nasopharyngeal Carcinoma Treatment.Nutlin-3 specifically targets p53-Mdm2 interaction offers new therapeutic opportunities by enhancing cancer cell growth arrest and apoptosis through the restoration of the p53-mediated tumor suppression pathway while producing minimal cytotoxicity and side effects. Nutlin-3 reverses the epithelial-mesenchymal transition in gemcitabine-resistant hepatocellular carcinoma cells.Nutlin-3 sensitizes nasopharyngeal carcinoma cells to cisplatin-induced cytotoxicity.

msds----Nutlin-3